They are defined as pituitary adenomas greater than 10 mm in size and are approximately twice as common as pituitary microadenomas. On imaging, they usually present as a solid tumor with attenuation similar to the brain HU and demonstrate moderate contrast enhancement. The same is observed on MRI, where they are isointense to the grey matter both on T1- and T2-weighted images. Patients typically present with symptoms of local mass effect on adjacent structures especially optic chiasm. Some may present hormonal imbalance, with symptoms of hypopituitarism from compression or secretion. Hormonal imbalance due to overproduction tends to present earlier and tumors are thus usually small at presentation.
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Introduction: Pituitary tumors comprise a quarter of the intracranial neoplasms and the adenomas represent the highest percentage of them. They are benign, but they can be invasive and they have an impact in morbidity and mortality. Objective: To analyze the clinical features of pituitary adenomas tumors, and create a computerized registry to improve strategies for diagnosis and monitoring of these patients.
Methods: A retrospective, descriptive analysis of medical records of a total of patients who attended the endocrinology service from to The variables were analyzed by the corresponding descriptive statistics.
The SPSS In all types the female group was predominant, except nonfunctioning. Conclusion: The findings are consistent with the literature in terms of frequency and age of onset of adenomas. We suggest the development of a registry to optimize the monitoring and treatment of patients, research and scientific publication.
Son de naturaleza benigna, pero pueden ser invasivos y producir impacto en la morbi-mortalidad. En todos los tipos el grupo femenino fue mayoritario, excepto en los no funcionantes.
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Abstract in English , Spanish. Similar articles Immunohistochemical detection of estrogen receptor alpha in pituitary adenomas and its correlation with cellular replication. Pereira-Lima JF, et al. Epub Apr PMID: Pituitary adenomas: results of surgically treated patients and review of the literature. Surg Neurol. PMID: Review. Surgical treatment of giant pituitary adenomas: strategies and results in a series of 95 consecutive patients.
Mortini P, et al. Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study. Daly AF, et al. J Clin Endocrinol Metab. Epub Aug 4. Nonfunctioning pituitary adenomas: the Oxford experience. Wass JA, Karavitaki N. Wass JA, et al. Nat Rev Endocrinol. Show more similar articles See all similar articles.
Cited by 1 article Binostril endoscopic transsphenoidal neurosurgery for pituitary adenomas: experience with 42 patients. Sun G, et al. Publication types English Abstract Actions. Adult Actions. Female Actions. Humans Actions. Male Actions.
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Although this distinction is largely arbitrary, it is commonly used and does highlight an important fact: small intrapituitary lesions microadenomas present differently and have different surgical and imaging challenges from larger lesions macroadenomas that extend into the suprasellar region. This article is a general overview. Pituitary adenomas are common, with rates varying widely depending on the definition: population prevalence is approximately 0. Pituitary adenomas present either due to hormonal imbalance both microadenomas and macroadenomas or mass effect on adjacent structures macroadenomas , classically the optic chiasm. Rarely presentation can be catastrophic, due to pituitary apoplexy. Over half of all adenomas are secretory 2 , although even when this is the case this may not be the cause of presentation.
[Pituitary Tumors: 10 Years of Experience]
It is a peer reviewed journal that offers free publication and free access. Papers from all over the world are most welcome, namely from Portuguese speaking countries. We accept manuscripts in Portuguese and English. We are planning to apply for Medline indexation, so join us and take part in this project. Send us interesting case reports, your original papers and reviews. Letters to the editor will be published in short time and papers will be published online as soon as they will be accepted. Pituitary apoplexy is a rare condition, with an estimated incidence of 0.
Introduction: Pituitary tumors comprise a quarter of the intracranial neoplasms and the adenomas represent the highest percentage of them. They are benign, but they can be invasive and they have an impact in morbidity and mortality. Objective: To analyze the clinical features of pituitary adenomas tumors, and create a computerized registry to improve strategies for diagnosis and monitoring of these patients. Methods: A retrospective, descriptive analysis of medical records of a total of patients who attended the endocrinology service from to The variables were analyzed by the corresponding descriptive statistics. The SPSS In all types the female group was predominant, except nonfunctioning.